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Nise oil also significantly enhanced the duration of the appearance of anoxic terminal negativity induced by oxygen withdrawal and inhibited induction of LTP in hippocampal slices. Conclusions: Our data indicate the anticonvulsant and neuroprotective effects of anise oil, likely via inhibition of synaptic plasticity. Further evaluation of anise oil to use in the treatment of neurological disorder

Ullin-repeats. Each of these repeats are composed of a five-helix structural motif in which the helices C to E are organized as a three-helix bundle that interacts with helices A and B to form the cullin repeat (Zheng et al., 2002b). Specifically the first repeat is responsible for binding the substrate adaptor complex of SkpCullin-based Ubiquitin E3 Ligases3 ofand the F-box protein, while the ot